4DKF
Crystal Structure of Human Interleukin-34 Bound to FAb2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Interleukin-34 | polymer | 190 | 21860.8 | 2 | UniProt (Q6ZMJ4) Pfam (PF15036) In PDB | Homo sapiens (human) | IL-34 |
2 | H, I | FAb2 Heavy Chain | polymer | 226 | 23764.4 | 2 | Homo sapiens (human) | ||
3 | L, M | FAb2 Light Chain | polymer | 214 | 23342.9 | 2 | Homo sapiens (human) | ||
4 | C, D | alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 2 | In PDB GlyTouCan (G08748CW) | |||
5 | water | water | 18.0 | 126 | Chemie (HOH) |
Sequence modifications
A, B: 21 - 193 (UniProt: Q6ZMJ4)
PDB | External Database | Details |
---|---|---|
Ala 18 | - | expression tag |
Gly 19 | - | expression tag |
Ser 20 | - | expression tag |
Gly 194 | - | expression tag |
Asn 195 | - | expression tag |
Ser 196 | - | expression tag |
Gly 197 | - | expression tag |
Asn 198 | - | expression tag |
Ser 199 | - | expression tag |
Asp 200 | - | expression tag |
Tyr 201 | - | expression tag |
Lys 202 | - | expression tag |
Asp 203 | - | expression tag |
Asp 204 | - | expression tag |
Asp 205 | - | expression tag |
Asp 206 | - | expression tag |
Lys 207 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 137936.2 | |
Branched | Number of molecules | 2 |
Total formula weight | 1821.6 | |
All* | Total formula weight | 139757.9 |