4DJP
Crystal Structure of wild-type HIV-1 Protease in Complex with MKP73
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Pol polyprotein | polymer | 99 | 10815.8 | 2 | UniProt (Q90K99) Pfam (PF00077) In PDB | Human immunodeficiency virus 1 | HIV-1 Protease |
2 | A | methyl (2S)-3-({[(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl][(2S)-2-methylbutyl]amino}-1-phenylbutan-2-yl]carbamoyl}oxy)-2-methylpropanoate | non-polymer | 564.7 | 1 | Chemie (M73) | |||
3 | B | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
4 | water | water | 18.0 | 197 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: Q90K99)
PDB | External Database | Details |
---|---|---|
Lys 7 | Gln 7 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 21631.6 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 754.6 | |
All* | Total formula weight | 22386.2 |