4DIH
X-ray structure of the complex between human alpha thrombin and thrombin binding aptamer in the presence of sodium ions
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | Prothrombin | polymer | 36 | 4096.5 | 1 | UniProt (P00734) Pfam (PF09396) | Homo sapiens (human) | Coagulation factor II, Thrombin light chain |
| 2 | B (H) | Prothrombin | polymer | 259 | 29780.2 | 1 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (human) | Coagulation factor II, Thrombin heavy chain |
| 3 | C (D) | Thrombin binding aptamer | polymer | 15 | 4743.1 | 1 | Synthetic DNA | ||
| 4 | D, H, I (L, H) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 5 | E (H) | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide | non-polymer | 454.0 | 1 | BIRD (PRD_000020) Chemie (0G6) | |||
| 6 | F (H) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 7 | G, L (H, D) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 8 | J, K (H) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 9 | M, N, O (L, H, D) | water | water | 18.0 | 217 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 38619.8 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 988.3 | |
| All* | Total formula weight | 39608.1 |
