4DH1
Low temperature X-ray structure of cAMP dependent Protein Kinase A catalytic subunit with low Mg2+, ATP and IP20
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | cAMP-dependent protein kinase catalytic subunit alpha | polymer | 350 | 40737.3 | 1 | UniProt (P05132) Pfam (PF00069) | Mus musculus (mouse) | PKA C-alpha |
| 2 | B (I) | cAMP-dependent protein kinase inhibitor alpha | polymer | 20 | 2226.4 | 1 | UniProt (P63248) | Mus musculus | PKI-alpha, cAMP-dependent protein kinase inhibitor, muscle/brain isoform |
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 5 | E, F (A, I) | water | water | 18.0 | 432 | Chemie (HOH) |
Sequence modifications
A: 15 - 350 (UniProt: P05132)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Asn 2 | - | expression tag |
| Ala 3 | - | expression tag |
| Ala 4 | - | expression tag |
| Ala 5 | - | expression tag |
| Ala 6 | - | expression tag |
| Lys 7 | - | expression tag |
| Lys 8 | - | expression tag |
| Gly 9 | - | expression tag |
| Ser 10 | - | expression tag |
| Glu 11 | - | expression tag |
| Gln 12 | - | expression tag |
| Glu 13 | - | expression tag |
| Ser 14 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42963.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 531.5 | |
| All* | Total formula weight | 43495.2 |
