4DF4
Crystal structure of the large fragment of DNA Polymerase I from Thermus aquaticus in a closed ternary complex with 7-(N-(10-hydroxydecanoyl)-aminopentinyl)-7-deaza-2 -dATP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase I, thermostable | polymer | 540 | 60937.0 | 1 | UniProt (P19821) Pfam (PF09281) Pfam (PF00476) | Thermus aquaticus | Taq polymerase 1 |
| 2 | B (B) | DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3') | polymer | 12 | 3617.4 | 1 | |||
| 3 | C (C) | DNA (5'-D(*AP*AP*AP*TP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3') | polymer | 16 | 4939.2 | 1 | |||
| 4 | D, E, H, I, J (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 5 | Chemie (MG) | |||
| 5 | F (A) | 7-{2-deoxy-5-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-erythro-pentofuranosyl}-5-{5-[(10-hydroxydecanoyl)amino]pent-1-yn-1-yl}-7H-pyrrolo[2,3-d]pyrimidin-4-amine | non-polymer | 741.6 | 1 | Chemie (0L3) | |||
| 6 | G (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 7 | K, L, M (A, B, C) | water | water | 18.0 | 356 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 69493.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 925.2 | |
| All* | Total formula weight | 70418.7 |
