4DBZ
Crystal Structure of V151L Actinorhodin Polyketide Ketoreductase with NADPH
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Ketoacyl reductase | polymer | 281 | 29478.4 | 2 | UniProt (P16544) Pfam (PF00106) In PDB | Streptomyces coelicolor | |
2 | A, B | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
3 | water | water | 18.0 | 44 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 261 (UniProt: P16544)
PDB | External Database | Details |
---|---|---|
Met -19 | - | expression tag |
Gly -18 | - | expression tag |
Ser -17 | - | expression tag |
Ser -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
Ser -9 | - | expression tag |
Ser -8 | - | expression tag |
Gly -7 | - | expression tag |
Leu -6 | - | expression tag |
Val -5 | - | expression tag |
Pro -4 | - | expression tag |
Arg -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Leu 151 | Val 151 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 58956.8 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1490.8 | |
All* | Total formula weight | 60447.6 |