4D7J
Structure of Bacillus subtilis nitric oxide synthase in complex with 6-(4-(((3-Fluorophenethyl)amino)methyl)phenyl)-4-methylpyridin-2- amine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NITRIC OXIDE SYNTHASE OXYGENASE | polymer | 363 | 41787.1 | 1 | UniProt (O34453) Pfam (PF02898) | BACILLUS SUBTILIS SUBSP. SUBTILIS STR. 168 | NOSOXY-LIKE PROTEIN, NITRIC OXIDE SYNTHASE |
| 2 | B (A) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
| 3 | C (A) | 5,6,7,8-TETRAHYDROBIOPTERIN | non-polymer | 241.2 | 1 | Chemie (H4B) | |||
| 4 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | E (A) | 6-[4-({[2-(3-fluorophenyl)ethyl]amino}methyl)phenyl]-4-methylpyridin-2-amine | non-polymer | 335.4 | 1 | Chemie (0GD) | |||
| 6 | F, G, H, K (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 7 | I (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 8 | J (A) | N-PROPANOL | non-polymer | 60.1 | 1 | Chemie (POL) | |||
| 9 | L (A) | water | water | 18.0 | 397 | Chemie (HOH) |
Sequence modifications
A: 1 - 363 (UniProt: O34453)
| PDB | External Database | Details |
|---|---|---|
| Ala 25 | Glu 25 | engineered mutation |
| Ala 26 | Glu 26 | engineered mutation |
| Ala 316 | Glu 316 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41787.1 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1763.2 | |
| All* | Total formula weight | 43550.3 |
