4D7I
Structure of Bacillus subtilis nitric oxide synthase I218V in complex with 6-(4-(((3-Fluorophenethyl)amino)methyl)phenyl)-4-methylpyridin-2- amine
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | NITRIC OXIDE SYNTHASE OXYGENASE | polymer | 363 | 41773.1 | 1 | UniProt (O34453) Pfam (PF02898) In PDB | BACILLUS SUBTILIS SUBSP. SUBTILIS STR. 168 | NOSOXY-LIKE PROTEIN, BACILLUS SUBTILIS NITRIC OXIDE SYNTHASE |
2 | A | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
3 | A | 5,6,7,8-TETRAHYDROBIOPTERIN | non-polymer | 241.2 | 1 | Chemie (H4B) | |||
4 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
5 | A | 6-[4-({[2-(3-fluorophenyl)ethyl]amino}methyl)phenyl]-4-methylpyridin-2-amine | non-polymer | 335.4 | 1 | Chemie (0GD) | |||
6 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
7 | water | water | 18.0 | 221 | Chemie (HOH) |
Sequence modifications
A: 1 - 363 (UniProt: O34453)
PDB | External Database | Details |
---|---|---|
Ala 25 | Glu 25 | engineered mutation |
Ala 26 | Glu 26 | engineered mutation |
Val 218 | Ile 218 | engineered mutation |
Ala 316 | Glu 316 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 41773.1 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 1320.7 | |
All* | Total formula weight | 43093.8 |