4D5N
Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1 | polymer | 436 | 49040.7 | 1 | UniProt (P62495) Pfam (PF03463) Pfam (PF03464) Pfam (PF03465) | HOMO SAPIENS (HUMAN) | EUKARYOTIC RELEASE FACTOR 1, ERF1, PROTEIN CL1, TB3-1, EUKARYORIC RELEASE FACTOR 1 |
| 2 | B (X) | CRICKET PARALYSIS VIRUS IRES RNA | polymer | 201 | 64363.9 | 1 | GenBank (8895506) | CRICKET PARALYSIS VIRUS |
Sequence modifications
A: 5 - 437 (UniProt: P62495)
X: 6030 - 6216 (GenBank: 8895506)
X: 6217 - 6230 (PDB: 4D5N)
| PDB | External Database | Details |
|---|---|---|
| Leu 438 | - | expression tag |
| Glu 439 | - | expression tag |
| His 440 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| A 6178 | U 6178 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 113404.6 | |
| All* | Total formula weight | 113404.6 |
