4D58
Focal Adhesion Kinase catalytic domain in complex with bis-anilino pyrimidine inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | FOCAL ADHESION KINASE | polymer | 276 | 31731.8 | 2 | UniProt (Q00944) Pfam (PF07714) | GALLUS GALLUS (CHICKEN) | FADK 1, FOCAL ADHESION KINASE-RELATED NONKINASE, FRNK, P41/ P43FRNK, PROTEIN-TYROSINE KINASE 2, P125FAK, PP125FAK |
| 2 | C, D, E (B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 3 | F (B) | 2-({5-CHLORO-2-[(2-METHOXY-4-MORPHOLIN-4-YLPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)-N-METHYLBENZAMIDE | non-polymer | 468.9 | 1 | Chemie (BI9) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 185 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63463.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 757.1 | |
| All* | Total formula weight | 64220.7 |
