4D4J
human PFKFB3 in complex with a pyrrolopyrimidone compound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 3 | polymer | 449 | 52066.5 | 1 | UniProt (Q16875) Pfam (PF01591) Pfam (PF00300) | HOMO SAPIENS (HUMAN) | 6PF-2-K/FRU-2\,6-P2ASE 3,PFKFBPASE 3 PFKFB3,6PF-2-K/FRU-2\,6-P2ASE BRAIN/PLACENTA-TYPE ISOZYME, RENAL CARCINOMA ANTIGEN NY-REN-56,IPFK-2,6-PHOSPHOFRUCTO-2-KINASE, FRUCTOSE-2\,6-BISPHOSPHATASE |
| 2 | B (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 3 | C (A) | PHOSPHONIC ACID | non-polymer | 82.0 | 1 | Chemie (PHS) | |||
| 4 | D (A) | 6-O-phosphono-beta-D-fructofuranose | non-polymer | 260.1 | 1 | Chemie (F6P) | |||
| 5 | E (A) | 5-(4-bromophenyl)-7-phenyl-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one | non-polymer | 366.2 | 1 | Chemie (BKI) | |||
| 6 | F (A) | water | water | 18.0 | 118 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 52066.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 803.3 | |
| All* | Total formula weight | 52869.8 |
