4D2R
Human IGF in complex with a Dyrk1B inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR | polymer | 302 | 34581.7 | 1 | UniProt (P08069) Pfam (PF07714) | HOMO SAPIENS (HUMAN) | INSULIN-LIKE GROWTH FACTOR RECEPTOR, INSULIN-LIKE GROWTH FAC IGF-I RECEPTOR, CD221, INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR BETA CHAIN |
| 2 | B (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 3 | C (A) | N-{2-methoxy-4-[(1-methylpiperidin-4-yl)oxy]phenyl}-4-(1H-pyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine | non-polymer | 430.5 | 1 | Chemie (DYK) | |||
| 4 | D (A) | water | water | 18.0 | 221 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34581.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 466.0 | |
| All* | Total formula weight | 35047.6 |
