4D2M

Vaccinia Virus F1L bound to Bim BH3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	PROTEIN F1	polymer	182	21566.4	2	UniProt (O57173) Pfam (PF11099) In PDB	VACCINIA VIRUS ANKARA
2	B, D	BCL-2-LIKE PROTEIN 11	polymer	26	3274.7	2	UniProt (O43521) Pfam (PF08945) In PDB	HOMO SAPIENS (HUMAN)	BCL2-L-11, BCL2-INTERACTING MEDIATOR OF CELL DEATH
3	A	(4R)-2-METHYLPENTANE-2,4-DIOL	non-polymer		118.2	1	Chemie (MRD)
4	A, C	CHLORIDE ION	non-polymer		35.5	4	Chemie (CL)
5		water	water		18.0	123	Chemie (HOH)

Sequence modifications

A, C: 18 - 186 (UniProt: O57173)

PDB	External Database	Details
Met 5	-	expression tag
Gly 6	-	expression tag
Ser 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
Ser 14	-	expression tag
Gln 15	-	expression tag
Asp 16	-	expression tag
Pro 17	-	expression tag
Phe 125	Ile 125	engineered mutation
Met 133	Leu 133	conflict
Leu 134	Met 134	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	49682.1
Non-Polymers*	Number of molecules	5
	Total formula weight	260.0
All*	Total formula weight	49942.1

*Water molecules are not included.