4D2L

Vaccinia Virus F1L bound to Bak BH3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	PROTEIN F1L	polymer	182	21490.3	1	UniProt (O57173) Pfam (PF11099)	VACCINIA VIRUS (STRAIN ANKARA) (VACV)
2	B (B)	BCL-2 HOMOLOGOUS ANTAGONIST/KILLER	polymer	26	2939.3	1	UniProt (Q16611)	HOMO SAPIENS (HUMAN)	APOPTOSIS REGULATOR BAK, BCL-2-LIKE PROTEIN 7, BCL2-L-7, F1L

Sequence modifications

A: 18 - 186 (UniProt: O57173)

PDB	External Database	Details
Met 5	-	expression tag
Gly 6	-	expression tag
Ser 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
Ser 14	-	expression tag
Gln 15	-	expression tag
Asp 16	-	expression tag
Pro 17	-	expression tag
Phe 125	Ile 125	engineered mutation
Met 133	Leu 133	conflict
Leu 134	Met 134	conflict

B: 51 - 75 (UniProt: Q16611)

PDB	External Database	Details
Lys 63	Ala 79	conflict
Gln 76	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	24429.5
All*	Total formula weight	24429.5

*Water molecules are not included.