4D1O

Structure of human endothelial nitric oxide synthase heme domain with L-Arg bound

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	NITRIC OXIDE SYNTHASE, ENDOTHELIAL	polymer	440	49345.8	2	UniProt (P29474) Pfam (PF02898) In PDB	HOMO SAPIENS (HUMAN)	CONSTITUTIVE NOS, CNOS, EC-NOS, ENDOTHELIAL NOS, ENOS, NOS TYPE III, NOSIII, CONSTITUTIVE NOS, NC-NOS, NOS TYPE I, NEURONAL NOS, N-NOS, NNOS, PEPTIDYL-CYSTEINE S-NITROSYLASE NOS1, BNOS, NEURONAL NITRIC OXIDE SYNTHASE, NITRIC OXIDE SYNTHASE, BRAIN
2	A, B	ARGININE	non-polymer		175.2	2	Chemie (ARG)
3	A, B	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	2	Chemie (HEM)
4	A, B	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
5	A, B	2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		209.2	4	Chemie (BTB)
6	A, B	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
7	A	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
8	A, B	5,6,7,8-TETRAHYDROBIOPTERIN	non-polymer		241.2	2	Chemie (H4B)
9	A, B	GADOLINIUM ATOM	non-polymer		157.3	2	Chemie (GD)
10		water	water		18.0	766	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	98691.5
Non-Polymers*	Number of molecules	18
	Total formula weight	3677.1
All*	Total formula weight	102368.7

*Water molecules are not included.