4D11
GalNAc-T2 crystal soaked with UDP-5SGalNAc, mEA2 peptide and manganese (Lower resolution dataset)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, D, E, F (A, B, D, E, F) | POLYPEPTIDE GALNAC-TRANSFERASE T2 | polymer | 571 | 64824.7 | 5 | UniProt (Q10471) Pfam (PF00535) Pfam (PF00652) | HOMO SAPIENS (HUMAN) | |
| 2 | C (C) | POLYPEPTIDE GALNAC-TRANSFERASE T2 | polymer | 571 | 64854.7 | 1 | UniProt (Q10471) Pfam (PF00535) Pfam (PF00652) | HOMO SAPIENS (HUMAN) | |
| 3 | G, H, I, J, K (L, O, P, X, Z) | PEPTIDE | polymer | 6 | 548.6 | 5 | UniProt (by SIFTS) (Q6FI18) | HOMO SAPIENS (HUMAN) | |
| 4 | L, O, R, T, W... (A, B, C, D, E...) | MANGANESE (II) ION | non-polymer | 54.9 | 6 | Chemie (MN) | |||
| 5 | M, P, V, X (A, B, D, E) | 2-acetamido-2-deoxy-5-thio-alpha-D-galactopyranose | non-polymer | 237.3 | 4 | Chemie (BBK) | |||
| 6 | AA, N, Q, S, U... (F, A, B, C, D...) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 6 | Chemie (UDP) |
Sequence modifications
A, B, D, E, F: 1 - 571 (UniProt: Q10471)
C: 1 - 571 (UniProt: Q10471)
| PDB | External Database | Details |
|---|---|---|
| Asp 516 | Asn 516 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ser 74 | Gly 74 | conflict |
| Asp 516 | Asn 516 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 11 |
| Total formula weight | 391721.3 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 3703.7 | |
| All* | Total formula weight | 395425.0 |
