4D0N
AKAP13 (AKAP-Lbc) RhoGEF domain in complex with RhoA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | TRANSFORMING PROTEIN RHOA | polymer | 185 | 20926.0 | 1 | UniProt (P61586) Pfam (PF00071) | HOMO SAPIENS (HUMAN) | RHOA, RHO CDNA CLONE 12, H12 |
| 2 | B (B) | A-KINASE ANCHOR PROTEIN 13 | polymer | 373 | 43442.6 | 1 | UniProt (Q12802) Pfam (PF00621) Pfam (PF00169) | HOMO SAPIENS (HUMAN) | AKAP13, AKAP-13, AKAP-LBC, BREAST CANCER NUCLEAR RECEPTOR-BINDING AUXILIARY PROTEIN, GUANINE NUCLEOTIDE EXCHANGE FACTOR LBC, HUMAN THYROID-ANCHORING PROTEIN 31, LYMPHOID BLAST CRISIS ONCOGENE, LBC ONCOGENE, NON-ONCOGENIC RHO GTPASE-SPECIFIC GTP EXCHANGE FACTOR, PROTEIN KINASE A-ANCHORING PROTEIN 13, PRKA13, P47 |
| 3 | C (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 4 | D, F, G, H, I (A, B) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 5 | E (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 6 | J, K (A, B) | water | water | 18.0 | 183 | Chemie (HOH) |
Sequence modifications
A: 1 - 184 (UniProt: P61586)
B: 1972 - 2342 (UniProt: Q12802)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 1970 | - | expression tag |
| Met 1971 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 64368.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 985.6 | |
| All* | Total formula weight | 65354.1 |
