4D0N
AKAP13 (AKAP-Lbc) RhoGEF domain in complex with RhoA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | TRANSFORMING PROTEIN RHOA | polymer | 185 | 20926.0 | 1 | UniProt (P61586) Pfam (PF00071) In PDB | HOMO SAPIENS (HUMAN) | RHOA, RHO CDNA CLONE 12, H12 |
| 2 | B | A-KINASE ANCHOR PROTEIN 13 | polymer | 373 | 43442.6 | 1 | UniProt (Q12802) Pfam (PF00621) Pfam (PF00169) In PDB | HOMO SAPIENS (HUMAN) | AKAP13, AKAP-13, AKAP-LBC, BREAST CANCER NUCLEAR RECEPTOR-BINDING AUXILIARY PROTEIN, GUANINE NUCLEOTIDE EXCHANGE FACTOR LBC, HUMAN THYROID-ANCHORING PROTEIN 31, LYMPHOID BLAST CRISIS ONCOGENE, LBC ONCOGENE, NON-ONCOGENIC RHO GTPASE-SPECIFIC GTP EXCHANGE FACTOR, PROTEIN KINASE A-ANCHORING PROTEIN 13, PRKA13, P47 |
| 3 | A | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 4 | A, B | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 5 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 6 | water | water | 18.0 | 183 | Chemie (HOH) |
Sequence modifications
A: 1 - 184 (UniProt: P61586)
B: 1972 - 2342 (UniProt: Q12802)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 1970 | - | expression tag |
| Met 1971 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 64368.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 985.6 | |
| All* | Total formula weight | 65354.1 |
