4CXQ

Mycobaterium tuberculosis transaminase BioA complexed with substrate KAPA

Replaces:  4MQN

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE	polymer	457	48536.5	2	UniProt (P0A4X6) Pfam (PF00202) UniProt (by SIFTS) (P9WQ81)	MYCOBACTERIUM TUBERCULOSIS	7,8-DIAMINO-PELARGONIC ACID AMINOTRANSFERASE, DAPA AT, DAPA AMINOTRANSFERASE, 7,8-DIAMINONONANOATE SYNTHASE, DANS, DIAMINOPEL ARGONIC ACID SYNTHASE, MYCOBACTERIUM TUBERCULOSIS BIOA
2	C, H (A, B)	PYRIDOXAL-5'-PHOSPHATE	non-polymer		247.1	2	Chemie (PLP)
3	D, I (A, B)	7-KETO-8-AMINOPELARGONIC ACID	non-polymer		187.2	2	Chemie (KAP)
4	E, J (A, B)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	2	Chemie (PEG)
5	F, G, K (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
6	L, M (A, B)	water	water		18.0	526	Chemie (HOH)

Sequence modifications

A, B: 1 - 437 (UniProt: P0A4X6)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	97073.0
Non-Polymers*	Number of molecules	9
	Total formula weight	1267.2
All*	Total formula weight	98340.2

*Water molecules are not included.