4CWP
Human HSP90 alpha N-terminal domain in complex with an Aminotriazoloquinazoline inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HEAT SHOCK PROTEIN HSP 90-ALPHA | polymer | 230 | 25810.9 | 1 | UniProt (P07900) Pfam (PF13589) | HOMO SAPIENS (HUMAN) | HEAT SHOCK 86 KDA, HSP 86, HSP86, RENAL CARCINOMA ANTIGEN NY-REN-38 |
| 2 | B (A) | 5-(1,3-benzodioxol-5-ylmethyl)[1,2,4]triazolo[1,5-c]quinazolin-2-amine | non-polymer | 319.3 | 1 | Chemie (TV2) | |||
| 3 | C (A) | water | water | 18.0 | 123 | Chemie (HOH) |
Sequence modifications
A: 9 - 236 (UniProt: P07900)
| PDB | External Database | Details |
|---|---|---|
| Gly 7 | - | expression tag |
| Pro 8 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 25810.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 319.3 | |
| All* | Total formula weight | 26130.3 |
