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4CVG

Structure of bovine endothelial nitric oxide synthase heme domain (H4B-free) supplemented with 50uM Zn acetate and with poor binding of 6-acetyl-2-amino-7,7-dimethyl-7,8-dihydropteridin-4(3H)-one.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
NITRIC OXIDE SYNTHASE, ENDOTHELIALpolymer44349727.02UniProt (P29473)
Pfam (PF02898)
BOS TAURUS (CATTLE)CONSTITUTIVE NOS, CNOS, EC-NOS, ENDOTHELIAL NOS, ENOS, NOS TYPE III, NOSIII
2C, G
(A, B)
ARGININEnon-polymer175.22Chemie (ARG)
3D, H
(A, B)
PROTOPORPHYRIN IX CONTAINING FEnon-polymer616.52Chemie (HEM)
4E, I
(A, B)
ACETATE IONnon-polymer59.02Chemie (ACT)
5F
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
6J
(B)
GLYCEROLnon-polymer92.11Chemie (GOL)
7K, L
(A, B)
waterwater18.0231Chemie (HOH)
Sequence modifications
A, B: 40 - 482 (UniProt: P29473)
PDBExternal DatabaseDetails
Arg 100Cys 100SEE REMARK 999
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight99454.0
Non-Polymers*Number of molecules8
Total formula weight1859.0
All*Total formula weight101313.0
*Water molecules are not included.

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PDB entries from 2025-07-23

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