4CUM
Structure of bovine endothelial nitric oxide synthase heme domain in complex with (9aS)-2-amino-9a-methyl-6,7,8,9,9a,10-hexahydrobenzo[g]pteridin-4(3H)-one
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | NITRIC OXIDE SYNTHASE, ENDOTHELIAL | polymer | 443 | 49727.0 | 2 | UniProt (P29473) Pfam (PF02898) | BOS TAURUS (CATTLE) | CONSTITUTIVE NOS, CNOS, EC-NOS, ENDOTHELIAL NOS, ENOS, NOS TYPE III, NOSIII, ENDOTHELIAL NITRIC OXIDE SYNTHASE |
| 2 | C, H (A, B) | ARGININE | non-polymer | 175.2 | 2 | Chemie (ARG) | |||
| 3 | D, I (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 4 | E, J (A, B) | (9aS)-2-amino-9a-methyl-6,7,8,9,9a,10-hexahydrobenzo[g]pteridin-4(3H)-one | non-polymer | 233.3 | 2 | Chemie (WS7) | |||
| 5 | F, K, L (A, B) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 6 | G (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 7 | M (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 8 | N, O (A, B) | water | water | 18.0 | 214 | Chemie (HOH) |
Sequence modifications
A, B: 40 - 482 (UniProt: P29473)
| PDB | External Database | Details |
|---|---|---|
| Arg 100 | Cys 100 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 99454.0 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 2384.6 | |
| All* | Total formula weight | 101838.6 |
