4CUE
Human Notch1 EGF domains 11-13 mutant T466V
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1 | polymer | 135 | 14855.6 | 1 | UniProt (P46531) Pfam (PF07645) Pfam (PF00008) | HOMO SAPIENS (HUMAN) | NOTCH 1, HN1, TRANSLOCATION-ASSOCIATED NOTCH PROTEIN TAN-1, HUMAN NOTCH |
| 2 | B, C, D (A) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 3 | E (A) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
A: 411 - 526 (UniProt: P46531)
| PDB | External Database | Details |
|---|---|---|
| Ser 409 | - | expression tag |
| Ala 410 | - | expression tag |
| Val 527 | - | expression tag |
| Asp 528 | - | expression tag |
| Leu 529 | - | expression tag |
| His 530 | - | expression tag |
| His 531 | - | expression tag |
| Ile 532 | - | expression tag |
| Leu 533 | - | expression tag |
| Asp 534 | - | expression tag |
| Ala 535 | - | expression tag |
| Gln 536 | - | expression tag |
| Lys 537 | - | expression tag |
| Met 538 | - | expression tag |
| Val 539 | - | expression tag |
| Trp 540 | - | expression tag |
| Asn 541 | - | expression tag |
| His 542 | - | expression tag |
| Arg 543 | - | expression tag |
| Val 466 | Thr 466 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14855.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 120.2 | |
| All* | Total formula weight | 14975.9 |
