4CTN
Glucopyranosylidene-spiro-iminothiazolidinone, a New Bicyclic Ring System: Synthesis, Derivatization, and Evaluation as Glycogen Phosphorylase Inhibitors by Enzyme Kinetic and Crystallographic Methods
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | GLYCOGEN PHOSPHORYLASE, MUSCLE FORM | polymer | 843 | 97422.4 | 1 | UniProt (P00489) Pfam (PF00343) | ORYCTOLAGUS CUNICULUS (RABBIT) | MYOPHOSPHORYLASE |
| 2 | B (A) | 2,3-DIHYDROXY-1,4-DITHIOBUTANE | non-polymer | 154.3 | 1 | Chemie (DTT) | |||
| 3 | C (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 4 | D (A) | N-[(2Z,5R,7R,8S,9S,10R)-8,9,10-trihydroxy-7-(hydroxymethyl)-4-oxo-6-oxa-1-thia-3-azaspiro[4.5]dec-2-ylidene]naphthalene-2-carboxamide | non-polymer | 418.4 | 1 | Chemie (M8P) | |||
| 5 | E (A) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 1 | Chemie (PLP) | |||
| 6 | F (A) | water | water | 18.0 | 163 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 97422.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 897.9 | |
| All* | Total formula weight | 98320.3 |
