4CQR

H5 (VN1194) Ser227Asn/Gln196Arg Mutant Haemagglutinin in Complex with Human Receptor Analogue 6'SLN

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Hemagglutinin HA1	polymer	326	37006.9	1	UniProt (Q6DQ34) Pfam (PF00509) In PDB	Influenza A virus (A/Vietnam/1194/2004(H5N1))
2	B	Hemagglutinin HA2	polymer	166	19098.0	1	UniProt (Q6DQ34) Pfam (PF00509) In PDB	Influenza A virus (A/Vietnam/1194/2004(H5N1))
3	C	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
4	D	beta-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	1	In PDB GlyTouCan (G42769XG)
5	E	N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose	branched		471.4	1	In PDB GlyTouCan (G63069TR)
6	F	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
7	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
8	B	3[N-MORPHOLINO]PROPANE SULFONIC ACID	non-polymer		209.3	1	Chemie (MPO)
9		water	water		18.0	72	Chemie (HOH)

Sequence modifications

A: 1 - 326 (UniProt: Q6DQ34)

PDB	External Database	Details
Arg 192	Gln 208	engineered mutation
Asn 223	Ser 239	engineered mutation
Thr 325	Arg 341	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	56104.8
Branched	Number of molecules	4
	Total formula weight	2393.2
Non-Polymers*	Number of molecules	3
	Total formula weight	651.7
All*	Total formula weight	59149.7

*Water molecules are not included.