4CQP
Crystal Structure of H5 (VN1194) Ser227Asn/Gln196Arg Mutant Haemagglutinin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Hemagglutinin HA1 | polymer | 326 | 37006.9 | 1 | UniProt (Q6DQ34) Pfam (PF00509) | Influenza A virus (A/Vietnam/1194/2004(H5N1)) | |
| 2 | B (B) | Hemagglutinin HA2 | polymer | 166 | 19098.0 | 1 | UniProt (Q6DQ34) Pfam (PF00509) | Influenza A virus (A/Vietnam/1194/2004(H5N1)) | |
| 3 | C (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 4 | D (D) | beta-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G66753FB) | |||
| 5 | E (E) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 6 | F, G (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 7 | H, I (A, B) | 3[N-MORPHOLINO]PROPANE SULFONIC ACID | non-polymer | 209.3 | 2 | Chemie (MPO) | |||
| 8 | J, K (A, B) | water | water | 18.0 | 23 | Chemie (HOH) |
Sequence modifications
A: 1 - 326 (UniProt: Q6DQ34)
| PDB | External Database | Details |
|---|---|---|
| Arg 192 | Gln 208 | engineered mutation |
| Asn 223 | Ser 239 | engineered mutation |
| Thr 325 | Arg 341 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 56104.8 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1921.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 860.9 | |
| All* | Total formula weight | 58887.6 |
