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4CMP

Crystal structure of S. pyogenes Cas9

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1polymer1372158986.12UniProt (Q99ZW2)
Pfam (PF16593)
Pfam (PF16592)
Pfam (PF13395)
Pfam (PF22702)
Pfam (PF16595)
STREPTOCOCCUS PYOGENESCAS9
2C, D, E, F, G
(A, B)
SULFATE IONnon-polymer96.15Chemie (SO4)
3H
(B)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
4I, J
(A, B)
waterwater18.0203Chemie (HOH)
Sequence modifications
A, B: 1 - 1368 (UniProt: Q99ZW2)
PDBExternal DatabaseDetails
Gly -3-expression tag
Ala -2-expression tag
Ala -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight317972.2
Non-Polymers*Number of molecules6
Total formula weight504.6
All*Total formula weight318476.8
*Water molecules are not included.

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PDB entries from 2025-06-18

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