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4CM0

Crystal structure of human soluble Adenylyl Cyclase with alpha,beta- methyleneadenosine-5'-triphosphate soaked with bicarbonate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
SOLUBLE ADENYLYL CYCLASEpolymer47554295.71UniProt (Q96PN6)
Pfam (PF00211)
HOMO SAPIENS (HUMAN)
2B
(A)
DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTERnon-polymer505.21Chemie (APC)
3C
(A)
CALCIUM IONnon-polymer40.11Chemie (CA)
4D
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
Sequence modifications
A: 1 - 469 (UniProt: Q96PN6)
PDBExternal DatabaseDetails
His 470-expression tag
His 471-expression tag
His 472-expression tag
His 473-expression tag
His 474-expression tag
His 475-expression tag
Pro 439Ala 439conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight54295.7
Non-Polymers*Number of molecules3
Total formula weight580.7
All*Total formula weight54876.4
*Water molecules are not included.

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PDB entries from 2025-06-18

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