4CLA
ALTERNATIVE BINDING MODES FOR CHLORAMPHENICOL AND 1-SUBSTITUTED CHLORAMPHENICOL ANALOGUES REVEALED BY SITE-DIRECTED MUTAGENESIS AND X-RAY CRYSTALLOGRAPHY OF CHLORAMPHENICOL ACETYLTRANSFERASE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | TYPE III CHLORAMPHENICOL ACETYLTRANSFERASE | polymer | 213 | 25055.5 | 1 | UniProt (P00484) Pfam (PF00302) | Escherichia coli | |
| 2 | B, C (A) | COBALT (II) ION | non-polymer | 58.9 | 2 | Chemie (CO) | |||
| 3 | D (A) | CHLORAMPHENICOL | non-polymer | 323.1 | 1 | Chemie (CLM) | |||
| 4 | E (A) | water | water | 18.0 | 203 | Chemie (HOH) |
Sequence modifications
A: 6 - 219 (UniProt: P00484)
| PDB | External Database | Details |
|---|---|---|
| Phe 160 | Leu 154 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 25055.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 441.0 | |
| All* | Total formula weight | 25496.5 |
