4CIA
Crystal structure of cathepsin A, complexed with compound 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | LYSOSOMAL PROTECTIVE PROTEIN | polymer | 455 | 51829.4 | 1 | UniProt (P10619) Pfam (PF00450) In PDB | HOMO SAPIENS (HUMAN) | CARBOXYPEPTIDASE C, CARBOXYPEPTIDASE L, CATHEPSIN A, PROTECTIVE PROTEIN CATHEPSIN A, PPCA, PROTECTIVE PROTEIN FOR BETA-GALACTOSIDASE |
| 2 | A | N-[(2S)-4-methyl-1-oxidanylidene-1-[[(1R,2S)-1-oxidanyl-1-(5-phenyl-1,2,4-oxadiazol-3-yl)butan-2-yl]amino]pentan-2-yl]morpholine-4-carboxamide | non-polymer | 459.5 | 1 | Chemie (6KZ) | |||
| 3 | A | CADMIUM ION | non-polymer | 112.4 | 7 | Chemie (CD) | |||
| 4 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 5 | water | water | 18.0 | 358 | Chemie (HOH) |
Sequence modifications
A: 1 - 452 (UniProt: P10619)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| Arg 0 | - | expression tag |
| Glu 453 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 51829.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1688.8 | |
| All* | Total formula weight | 53518.2 |
