4CFT
Structure of bovine endothelial nitric oxide synthase heme domain in complex with 7-((3-Fluorophenethylamino)ethyl)quinolin-2-amine
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | ENDOTHELIAL NITRIC OXIDE SYNTHASE | polymer | 443 | 49727.0 | 1 | UniProt (P29473) Pfam (PF02898) In PDB | BOS TAURUS (CATTLE) | CONSTITUTIVE NOS, CNOS, EC-NOS, ENDOTHELIAL NOS, ENOS, NOS TYPE III, NOSIII, ENDOTHELIAL NITRIC OXIDE SYNTHASE |
2 | B | ENDOTHELIAL NITRIC OXIDE SYNTHASE | polymer | 443 | 49623.0 | 1 | UniProt (P29473) Pfam (PF02898) In PDB | BOS TAURUS (CATTLE) | CONSTITUTIVE NOS, CNOS, EC-NOS, ENDOTHELIAL NOS, ENOS, NOS TYPE III, NOSIII, ENDOTHELIAL NITRIC OXIDE SYNTHASE |
3 | A, B | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
4 | A, B | 5,6,7,8-TETRAHYDROBIOPTERIN | non-polymer | 241.2 | 2 | Chemie (H4B) | |||
5 | A, B | 7-[2-[2-(3-fluorophenyl)ethylamino]ethyl]quinolin-2-amine | non-polymer | 309.4 | 2 | Chemie (M48) | |||
6 | A, B | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) | |||
7 | A, B | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
8 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
9 | water | water | 18.0 | 325 | Chemie (HOH) |
Sequence modifications
A: 40 - 482 (UniProt: P29473)
B: 40 - 482 (UniProt: P29473)
PDB | External Database | Details |
---|---|---|
Arg 100 | Cys 100 | conflict |
PDB | External Database | Details |
---|---|---|
Arg 100 | Cys 100 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 99350.0 | |
Non-Polymers* | Number of molecules | 13 |
Total formula weight | 2820.0 | |
All* | Total formula weight | 102170.0 |