4CDE

Human DPP1 in complex with 4-amino-N-((1S)-1-cyano-2-(4-(4- cyanophenyl)phenyl)ethyl)tetrahydropyran-4-carboxamide

Entity

Chain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
A, DDIPEPTIDYL PEPTIDASE 1 EXCLUSION DOMAIN CHAINpolymer11913500.22
UniProt (P53634)
Pfam (PF08773)
HOMO SAPIENS (HUMAN)@PDBjDIPEPTIDYL PEPTIDASE I EXCLUSION DOMAIN CHAIN, CATHEPSIN C, CATHEPSIN J, DIPEPTIDYL PEPTIDASE I, DPP-I, DPPI, DIPEPTIDYL TRANSFERASE
B, EDIPEPTIDYL PEPTIDASE 1 HEAVY CHAINpolymer16518630.02
UniProt (P53634)
HOMO SAPIENS (HUMAN)@PDBjDIPEPTIDYL PEPTIDASE I HEAVY CHAIN, CATHEPSIN C, CATHEPSIN J, DIPEPTIDYL PEPTIDASE I, DPP-I, DPPI, DIPEPTIDYL TRANSFERASE
C, FDIPEPTIDYL PEPTIDASE 1 LIGHT CHAINpolymer697583.42
UniProt (P53634)
HOMO SAPIENS (HUMAN)@PDBjDIPEPTIDYL PEPTIDASE I LIGHT CHAIN, CATHEPSIN C, CATHEPSIN J, DIPEPTIDYL PEPTIDASE I, DPP-I, DPPI, DIPEPTIDYL TRANSFERASE
N-ACETYL-D-GLUCOSAMINEnon-polymer221.24
4-AZANYL-N-[(2S)-1-AZANYLIDENE-3-[4-(4-CYANOPHENYL)PHENYL]PROPAN-2-YL]OXANE-4-CARBOXAMIDEnon-polymer376.52
CHLORIDE IONnon-polymer35.52
waterwater18.0142

Sequence viewer

Contents of the asymmetric unit

PolymersNumber of chains6
Total molecular weight79427.3
Non-Polymers*Number of molecules8
Total molecular weight1708.6
All*Total molecular weight81135.9
*Water molecules are not included.