4CDD
Human DPP1 in complex with (2S)-N-((1S)-1-cyano-2-(4-(4-cyanophenyl) phenyl)ethyl)piperidine-2-carboxamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | DIPEPTIDYL PEPTIDASE 1 EXCLUSION DOMAIN CHAIN | polymer | 120 | 13601.3 | 2 | UniProt (P53634) Pfam (PF08773) | HOMO SAPIENS (HUMAN) | DIPEPTIDYL PEPTIDASE I EXCLUSION DOMAIN CHAIN, CATHEPSIN C, CATHEPSIN J, DIPEPTIDYL PEPTIDASE I, DPP-I, DPPI, DIPEPTIDYL TRANSFERASE |
| 2 | B, E (B, E) | DIPEPTIDYL PEPTIDASE 1 HEAVY CHAIN | polymer | 165 | 18630.0 | 2 | UniProt (P53634) Pfam (PF00112) | HOMO SAPIENS (HUMAN) | DIPEPTIDYL PEPTIDASE I HEAVY CHAIN, CATHEPSIN C, CATHEPSIN J, DIPEPTIDYL PEPTIDASE I, DPP-I, DPPI, DIPEPTIDYL TRANSFERASE |
| 3 | C, F (C, F) | DIPEPTIDYL PEPTIDASE 1 LIGHT CHAIN | polymer | 69 | 7583.4 | 2 | UniProt (P53634) | HOMO SAPIENS (HUMAN) | DIPEPTIDYL PEPTIDASE I LIGHT CHAIN, CATHEPSIN C, CATHEPSIN J, DIPEPTIDYL PEPTIDASE I, DPP-I, DPPI, DIPEPTIDYL TRANSFERASE |
| 4 | G (G) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | H, I, L (A, B, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 6 | J, M (B, E) | (2S)-N-[(2S)-1-AZANYLIDENE-3-[4-(4-CYANOPHENYL)PHENYL]PROPAN-2-YL]PIPERIDINE-2-CARBOXAMIDE | non-polymer | 360.5 | 2 | Chemie (GDI) | |||
| 7 | K, N (B, E) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 8 | O, P, Q, R, S (A, B, C, D, E) | water | water | 18.0 | 94 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 79629.5 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1455.4 | |
| All* | Total formula weight | 81509.3 |
