4CCC
STRUCTURE OF MOUSE GALACTOCEREBROSIDASE WITH 4NBDG: ENZYME-SUBSTRATE COMPLEX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | GALACTOCEREBROSIDASE | polymer | 654 | 74596.8 | 1 | UniProt (P54818) Pfam (PF02057) Pfam (PF17387) Pfam (PF21708) | MUS MUSCULUS (HOUSE MOUSE) | GALCERASE, GALACTOCEREBROSIDE BETA-GALACTOSIDASE, GALACTOSYLCERAMIDASE, GALACTOSYLCERAMIDE BETA-GALACTOSIDASE, BETA-GALACTOCEREBROSIDASE, GALC |
| 2 | B, C, D (B, C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 3 | E (A) | 4-nitrophenyl beta-D-galactopyranoside | non-polymer | 301.2 | 1 | Chemie (147) | |||
| 4 | F (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | G (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 6 | H (A) | water | water | 18.0 | 272 | Chemie (HOH) |
Sequence modifications
A: 25 - 668 (UniProt: P54818)
| PDB | External Database | Details |
|---|---|---|
| His 15 | - | expression tag |
| His 16 | - | expression tag |
| His 17 | - | expression tag |
| His 18 | - | expression tag |
| His 19 | - | expression tag |
| His 20 | - | expression tag |
| Ile 21 | - | expression tag |
| Glu 22 | - | expression tag |
| Gly 23 | - | expression tag |
| Arg 24 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 74596.8 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1273.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 562.5 | |
| All* | Total formula weight | 76432.5 |
