4CBN
Crystal structure of Complement Factor D mutant R202A after conventional refinement
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | COMPLEMENT FACTOR D | polymer | 228 | 24352.7 | 2 | UniProt (P00746) Pfam (PF00089) | HOMO SAPIENS (HUMAN) | ADIPSIN, C3 CONVERTASE ACTIVATOR, PROPERDIN FACTOR D |
| 2 | C, D, E (A, B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 3 | F, G (A, B) | water | water | 18.0 | 308 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 228 (UniProt: P00746)
| PDB | External Database | Details |
|---|---|---|
| Ala 202 | Arg 227 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 48705.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 276.3 | |
| All* | Total formula weight | 48981.7 |
