4CBL

Pestivirus NS3 helicase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	SERINE PROTEASE NS3	polymer	509	57220.2	4	UniProt (P19712) Pfam (PF07652) Pfam (PF00271) Pfam (PF20907)	CLASSICAL SWINE FEVER VIRUS	NON-STRUCTURAL PROTEIN 3

Sequence modifications

A, B, C, D: 203 - 691 (UniProt: P19712)

PDB	External Database	Details
Met 183	-	expression tag
Ala 184	-	expression tag
Ser 185	-	expression tag
His 186	-	expression tag
His 187	-	expression tag
His 188	-	expression tag
His 189	-	expression tag
His 190	-	expression tag
His 191	-	expression tag
His 192	-	expression tag
Met 193	-	expression tag
Ser 194	-	expression tag
Gly 195	-	expression tag
Ile 196	-	expression tag
Gln 197	-	expression tag
Thr 198	-	expression tag
Val 199	-	expression tag
Ser 200	-	expression tag
Lys 201	-	expression tag
Ser 202	-	expression tag
Tyr 588	Asn 2177	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	228880.8
All*	Total formula weight	228880.8

*Water molecules are not included.