4CB7
Structure of Influenza A H5N1 PB2 cap-binding domain with bound cap analogue (compound 8e)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | POLYMERASE BASIC SUBUNIT 2 | polymer | 163 | 18248.2 | 2 | UniProt (Q2LG68) Pfam (PF00604) In PDB | INFLUENZA A VIRUS | POLYMERASE PB2 SUBUNIT |
| 2 | A, B | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 3 | B | 5-[2-(2-azanyl-7-methyl-6-oxidanylidene-1H-purin-9-ium-9-yl)ethanoyl]-2-oxidanyl-benzoic acid | non-polymer | 344.3 | 1 | Chemie (41G) | |||
| 4 | water | water | 18.0 | 129 | Chemie (HOH) |
Sequence modifications
A, B: 318 - 479 (UniProt: Q2LG68)
| PDB | External Database | Details |
|---|---|---|
| Gly 317 | - | expression tag |
| Gly 421 | Val 421 | engineered mutation |
| - | Asn 422 | deletion |
| - | Arg 423 | deletion |
| - | Ala 424 | deletion |
| - | Asn 425 | deletion |
| Ser 422 | Gln 426 | engineered mutation |
| Gly 423 | Arg 427 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36496.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 712.7 | |
| All* | Total formula weight | 37209.1 |
