4CAJ

Crystallographic structure of the mouse SIGN-R1 CRD domain in complex with sialic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	CD209 ANTIGEN-LIKE PROTEIN B	polymer	158	17973.3	4	UniProt (Q8CJ91) Pfam (PF00059)	MUS MUSCULUS (HOUSE MOUSE)	DC-SIGN-RELATED PROTEIN 1, DC-SIGNR1, OTB7, SIGN-R1
2	E, KA, Q, Z (A, D, B, C)	CALCIUM ION	non-polymer		40.1	4	Chemie (CA)
3	AA, BA, CA, DA, F... (C, A, D, B)	SULFATE ION	non-polymer		96.1	30	Chemie (SO4)
4	EA, I, U (C, A, B)	N-acetyl-alpha-neuraminic acid	non-polymer		309.3	3	Chemie (SIA)
5	FA, J (C, A)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
6	RA, SA, TA, UA (A, B, C, D)	water	water		18.0	466	Chemie (HOH)

Sequence modifications

A, B, C, D: 191 - 325 (UniProt: Q8CJ91)

PDB	External Database	Details
Met 168	-	expression tag
Ser 169	-	expression tag
Ala 170	-	expression tag
Leu 171	-	expression tag
Leu 172	-	expression tag
Ile 173	-	expression tag
Leu 174	-	expression tag
Ala 175	-	expression tag
Leu 176	-	expression tag
Val 177	-	expression tag
Gly 178	-	expression tag
Ala 179	-	expression tag
Ala 180	-	expression tag
Val 181	-	expression tag
Ala 182	-	expression tag
Asp 183	-	expression tag
Tyr 184	-	expression tag
Lys 185	-	expression tag
Asp 186	-	expression tag
Asp 187	-	expression tag
Asp 188	-	expression tag
Asp 189	-	expression tag
Lys 190	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	71893.2
Non-Polymers*	Number of molecules	39
	Total formula weight	4040.9
All*	Total formula weight	75934.1

*Water molecules are not included.