4C99

Mouse ZNRF3 ectodomain in complex with mouse RSPO2 Fu1-Fu2 crystal form I

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	E3 UBIQUITIN-PROTEIN LIGASE ZNRF3	polymer	165	18203.6	2	UniProt (Q5SSZ7) Pfam (PF18212) In PDB	MUS MUSCULUS (HOUSE MOUSE)	ZINC/RING FINGER PROTEIN 3, ZNRF3
2	B, D	R-SPONDIN-2	polymer	122	14158.1	2	UniProt (Q8BFU0) Pfam (PF15913) In PDB	MUS MUSCULUS (HOUSE MOUSE)	CYSTEINE-RICH AND SINGLE THROMBOSPONDIN DOMAIN-CONTAINING PR
3	A	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)

Sequence modifications

A, C: 53 - 205 (UniProt: Q5SSZ7)

PDB	External Database	Details
Glu 50	-	expression tag
Thr 51	-	expression tag
Gly 52	-	expression tag
Gly 206	-	expression tag
Thr 207	-	expression tag
Lys 208	-	expression tag
His 209	-	expression tag
His 210	-	expression tag
His 211	-	expression tag
His 212	-	expression tag
His 213	-	expression tag
His 214	-	expression tag

B, D: 37 - 144 (UniProt: Q8BFU0)

PDB	External Database	Details
Glu 34	-	expression tag
Thr 35	-	expression tag
Gly 36	-	expression tag
Thr 145	-	expression tag
His 146	-	expression tag
His 147	-	expression tag
His 148	-	expression tag
His 149	-	expression tag
His 150	-	expression tag
His 151	-	expression tag
His 152	-	expression tag
His 153	-	expression tag
His 154	-	expression tag
His 155	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	64723.3
Non-Polymers*	Number of molecules	1
	Total formula weight	35.5
All*	Total formula weight	64758.7

*Water molecules are not included.