4C7W
Crystal structure of Mouse Hepatitis virus strain S Hemagglutinin- esterase in complex with 4-O-acetylated sialic acid
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | HEMAGGLUTININ-ESTERASE | polymer | 386 | 43503.4 | 2 | UniProt (O55252) Pfam (PF03996) Pfam (PF02710) UniProt (by SIFTS) (P31614) In PDB | MURINE HEPATITIS VIRUS | |
2 | C, E, G, I | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
3 | D, F, H | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
4 | J | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1235.1 | 1 | In PDB GlyTouCan (G55220VL) | |||
5 | A, B | methyl 4,9-di-O-acetyl-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosidonic acid | non-polymer | 407.4 | 2 | Chemie (SIO) | |||
6 | A, B | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
7 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
8 | B | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
9 | water | water | 18.0 | 75 | Chemie (HOH) |
Sequence modifications
A, B: 25 - 403 (UniProt: O55252)
PDB | External Database | Details |
---|---|---|
Ala 45 | Ser 45 | engineered mutation |
Ser 404 | - | expression tag |
Asp 405 | - | expression tag |
Pro 406 | - | expression tag |
Leu 407 | - | expression tag |
Val 408 | - | expression tag |
Pro 409 | - | expression tag |
Arg 410 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 87006.7 | |
Branched | Number of molecules | 8 |
Total formula weight | 4692.3 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 1869.9 | |
All* | Total formula weight | 93568.9 |