4C79

Crystal structure of the Smoothened CRD, native

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	SMOOTHENED	polymer	193	22144.2	2	UniProt (Q90X26) Pfam (PF01392) UniProt (by SIFTS) (Q5RH73) In PDB	DANIO RERIO (ZEBRAFISH)
2	A	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
3	A, B	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
4		water	water		18.0	48	Chemie (HOH)

Sequence modifications

A, B: 28 - 210 (UniProt: Q90X26)

PDB	External Database	Details
Met 27	-	expression tag
Lys 211	-	expression tag
Leu 212	-	expression tag
Glu 213	-	expression tag
His 214	-	expression tag
His 215	-	expression tag
His 216	-	expression tag
His 217	-	expression tag
His 218	-	expression tag
His 219	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	44288.3
Non-Polymers*	Number of molecules	3
	Total formula weight	111.4
All*	Total formula weight	44399.7

*Water molecules are not included.