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4C6P

Crystal structure of the dihydroorotase domain of human CAD C1613S mutant in apo-form at pH 7.0

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
CAD PROTEINpolymer39342900.01UniProt (P27708)
Pfam (PF01979)
HOMO SAPIENS (HUMAN)DIHYDROOROTASE
2B, C, D
(A)
ZINC IONnon-polymer65.43Chemie (ZN)
3E, F, G, H
(A)
FORMIC ACIDnon-polymer46.04Chemie (FMT)
4I
(A)
waterwater18.0400Chemie (HOH)
Sequence modifications
A: 1456 - 1846 (UniProt: P27708)
PDBExternal DatabaseDetails
Gly 1454-expression tag
Pro 1455-expression tag
Ser 1613Cys 1613engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight42900.0
Non-Polymers*Number of molecules7
Total formula weight380.3
All*Total formula weight43280.3
*Water molecules are not included.

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PDB entries from 2025-06-25

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