4C5R

Structural Investigations into the Stereochemistry and Activity of a Phenylalanine-2,3-Aminomutase from Taxus chinensis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	PHENYLALANINE AMMONIA-LYASE	polymer	707	77553.6	4	UniProt (Q68G84) Pfam (PF00221)	TAXUS WALLICHIANA VAR. CHINENSIS	PHENYLALANINE AMINOMUTASE
2	E, G, I, J (A, B, C, D)	(3S)-3-amino-2,2-difluoro-3-phenylpropanoic acid	non-polymer		201.2	4	Chemie (BQ7)
3	F, H (A, B)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
4	K, L, M, N (A, B, C, D)	water	water		18.0	641	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 687 (UniProt: Q68G84)

PDB	External Database	Details
Mdo 175	Ala 175	chromophore
Mdo 175	Ser 176	chromophore
Mdo 175	Gly 177	chromophore
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	310214.5
Non-Polymers*	Number of molecules	6
	Total formula weight	988.9
All*	Total formula weight	311203.4

*Water molecules are not included.