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4C58

Structure of GAK kinase in complex with nanobody (NbGAK_4)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Cyclin-G-associated kinasepolymer34038183.61UniProt (O14976)
Pfam (PF00069)
Homo sapiens (Human)
2B
(B)
nanobodypolymer14015085.51Lama glama (Llama)
3C, D, F
(A, B)
1,2-ETHANEDIOLnon-polymer62.13Chemie (EDO)
4E
(A)
9-HYDROXY-4-PHENYLPYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONEnon-polymer328.31Chemie (824)
5G, H
(A, B)
waterwater18.0194Chemie (HOH)
Sequence modifications
A: 14 - 351 (UniProt: O14976)
PDBExternal DatabaseDetails
Ser 12-expression tag
Met 13-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight53269.1
Non-Polymers*Number of molecules4
Total formula weight514.5
All*Total formula weight53783.6
*Water molecules are not included.

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PDB entries from 2025-06-18

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