4C49
Reactive loop cleaved human CBG in complex with cortisol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | CORTICOSTEROID-BINDING GLOBULIN | polymer | 373 | 41625.4 | 4 | UniProt (P08185) Pfam (PF00079) | HOMO SAPIENS (HUMAN) | CBG, SERPIN A6, TRANSCORTIN |
| 2 | E, F, G, H (A, B, C, D) | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione | non-polymer | 362.5 | 4 | Chemie (HCY) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 38 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 11 - 383 (UniProt: P08185)
| PDB | External Database | Details |
|---|---|---|
| Arg 349 | Thr 371 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 166501.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1449.8 | |
| All* | Total formula weight | 167951.5 |
