4C49
Reactive loop cleaved human CBG in complex with cortisol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | CORTICOSTEROID-BINDING GLOBULIN | polymer | 373 | 41625.4 | 4 | UniProt (P08185) Pfam (PF00079) | HOMO SAPIENS (HUMAN) | CBG, SERPIN A6, TRANSCORTIN |
| 2 | E, F, G, H (A, B, C, D) | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione | non-polymer | 362.5 | 4 | Chemie (HCY) PubChem (16757875) PubChem (16760505) PubChem (17749280) PubChem (18635646) PubChem (3640) PubChem (5754) PubChem (176519891) PubChem (22841298) PubChem (108888) PubChem (23766831) PubChem (16401107) PubChem (24867549) PubChem (40469544) PubChem (40469545) PubChem (40488894) PubChem (40543465) PubChem (40543468) PubChem (40543471) PubChem (40543474) PubChem (40776161) PubChem (44656583) PubChem (1768391) PubChem (1768392) PubChem (1768390) PubChem (46885418) PubChem (46907807) PubChem (657311) PubChem (50987195) PubChem (50987424) PubChem (969496) PubChem (56614803) PubChem (56635598) PubChem (1350204) PubChem (57232608) PubChem (3246033) PubChem (57536781) PubChem (59582250) PubChem (60111544) PubChem (5320346) PubChem (6603869) PubChem (6713680) PubChem (229860) PubChem (7048969) PubChem (7067813) PubChem (89693181) PubChem (8015711) PubChem (11279933) PubChem (1403277) PubChem (11869394) PubChem (11869395) PubChem (11869396) PubChem (12304007) PubChem (12304008) PubChem (12304009) PubChem (12304012) PubChem (12304023) PubChem (6336184) PubChem (101739542) PubChem (6981543) PubChem (7059531) PubChem (122664736) PubChem (12304018) PubChem (124351407) PubChem (124404247) PubChem (124514954) PubChem (124746079) PubChem (125037485) PubChem (129009993) PubChem (129010215) PubChem (132012242) PubChem (154825154) PubChem (159059490) PubChem (162927257) PubChem (162927258) PubChem (165944364) PubChem (166480825) PubChem (169428820) PubChem (172400002) PubChem (172873892) PubChem (173540535) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 38 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 11 - 383 (UniProt: P08185)
| PDB | External Database | Details |
|---|---|---|
| Arg 349 | Thr 371 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 166501.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1449.8 | |
| All* | Total formula weight | 167951.5 |
