4C2Q
Crystal structure of human testis angiotensin-I converting enzyme mutant R522K
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ANGIOTENSIN-CONVERTING ENZYME | polymer | 589 | 68040.9 | 1 | UniProt (P12821) Pfam (PF01401) | HOMO SAPIENS (HUMAN) | ACE, DIPEPTIDYL CARBOXYPEPTIDASE I, KININASE II, CD143, ANGIOTENSIN-CONVERTING ENZYME\,SOLUBLE FORM, ANGIOTENSIN-I CONVERTING ENZYME |
| 2 | B (B) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G32152BH) | |||
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | E (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | F (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 7 | G (A) | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL | non-polymer | 354.4 | 1 | Chemie (PE4) | |||
| 8 | H (A) | water | water | 18.0 | 109 | Chemie (HOH) |
Sequence modifications
A: 37 - 625 (UniProt: P12821)
| PDB | External Database | Details |
|---|---|---|
| Lys 522 | Arg 553 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 68040.9 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 732.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 610.4 | |
| All* | Total formula weight | 69384.0 |
