4C2P
Crystal structure of human testis angiotensin-I converting enzyme mutant R522K in complex with captopril
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | ANGIOTENSIN-CONVERTING ENZYME | polymer | 589 | 68040.9 | 1 | UniProt (P12821) Pfam (PF01401) In PDB | HOMO SAPIENS (HUMAN) | ACE, DIPEPTIDYL CARBOXYPEPTIDASE I, KININASE II, CD143, ANGIOTENSIN-CONVERTING ENZYME, SOLUBLE FORM |
| 2 | B | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G32152BH) | |||
| 3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | A | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | A | L-CAPTOPRIL | non-polymer | 217.3 | 1 | Chemie (X8Z) | |||
| 6 | A | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 7 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 8 | water | water | 18.0 | 356 | Chemie (HOH) |
Sequence modifications
A: 37 - 625 (UniProt: P12821)
| PDB | External Database | Details |
|---|---|---|
| Lys 522 | Arg 553 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 68040.9 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 732.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 504.7 | |
| All* | Total formula weight | 69278.3 |
