4BXS
Crystal Structure of the Prothrombinase Complex from the Venom of Pseudonaja Textilis
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | FACTOR X-LIKE PROTEASE | polymer | 423 | 47041.3 | 1 | UniProt (Q6IT10) Pfam (PF00594) Pfam (PF00008) Pfam (PF14670) Pfam (PF00089) UniProt (by SIFTS) (Q56VR3) | PSEUDONAJA TEXTILIS (AUSTRALIAN EASTERN BROWN SNAKE) | FACTOR X |
| 2 | B (V) | VENOM PROTHROMBIN ACTIVATOR PSEUTARIN-C NON-CATALYTIC SUBUNIT | polymer | 1430 | 162826.8 | 1 | UniProt (Q7SZN0) Pfam (PF07732) Pfam (PF00754) | PSEUDONAJA TEXTILIS (AUSTRALIAN EASTERN BROWN SNAKE) | FACTOR V, PCNS, VPA, VENOM COAGULATION FACTOR VA-LIKE PROTEIN, PSEUTARIN-C NON-CATALYTIC SUBUNIT HEAVY CHAIN, PSEUTARIN-C NON-CATALYTIC SUBUNIT LIGHT CHAIN |
| 3 | C (B) | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 1 | In PDB GlyTouCan (G86851RC) | |||
| 4 | D (C) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1397.2 | 1 | In PDB GlyTouCan (G80966KZ) | |||
| 5 | E, F (D, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 6 | G (V) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 7 | H, I (V) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 8 | J (V) | COPPER (II) ION | non-polymer | 63.5 | 1 | Chemie (CU) | |||
| 9 | K, L (A, V) | water | water | 18.0 | 112 | Chemie (HOH) |
Sequence modifications
V: 1 - 1430 (UniProt: Q7SZN0)
| PDB | External Database | Details |
|---|---|---|
| Lys 50 | Glu 80 | conflict |
| Lys 1287 | Ser 1317 | conflict |
| Phe 1305 | Ser 1335 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 209868.1 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 2613.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 364.9 | |
| All* | Total formula weight | 212846.4 |
