4BWN

NEMO CC2-LZ DOMAIN

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	NF-KAPPA-B ESSENTIAL MODULATOR	polymer	110	12809.5	2	UniProt (Q9Y6K9) Pfam (PF16516)	HOMO SAPIENS (HUMAN)	NEMO, FIP-3, IKB KINASE-ASSOCIATED PROTEIN 1, IKKAP1, INHIB ITOR OF NUCLEAR FACTOR KAPPA-B KINASE SUBUNIT GAMMA, I-KAPPA-B KIN ASE SUBUNIT GAMMA, IKK-GAMMA, IKKG, IKB KINASE SUBUNIT GAMMA, NF-K APPA-B ESSENTIAL MODIFIER, NEMO
2	C, D (A, B)	water	water		18.0	25	Chemie (HOH)

Sequence modifications

A, B: 258 - 344 (UniProt: Q9Y6K9)

PDB	External Database	Details
Met 235	-	expression tag
Gly 236	-	expression tag
Ser 237	-	expression tag
Ser 238	-	expression tag
His 239	-	expression tag
His 240	-	expression tag
His 241	-	expression tag
His 242	-	expression tag
His 243	-	expression tag
His 244	-	expression tag
Ser 245	-	expression tag
Ser 246	-	expression tag
Gly 247	-	expression tag
Leu 248	-	expression tag
Val 249	-	expression tag
Pro 250	-	expression tag
Arg 251	-	expression tag
Gly 252	-	expression tag
Ser 253	-	expression tag
His 254	-	expression tag
Met 255	-	expression tag
Ala 256	-	expression tag
Arg 257	-	expression tag
Asn 292	Lys 292	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	25619.0
All*	Total formula weight	25619.0

*Water molecules are not included.