4BWB
Structure of Evolved Agonist-bound Neurotensin Receptor 1 Mutant without Lysozyme Fusion
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | NEUROTENSIN RECEPTOR TYPE 1 | polymer | 338 | 37598.1 | 2 | UniProt (P20789) Pfam (PF00001) In PDB | RATTUS NORVEGICUS (NORWAY RAT) | NT-R-1, NTR1, HIGH-AFFINITY LEVOCABASTINE-INSENSITIVE NEUROTENSIN RECEPTOR, NTRH, NEUROTENSIN RECEPTOR 1 HTGH4DIC3A |
2 | C, D | NEUROTENSIN | polymer | 10 | 1087.3 | 2 | UniProt (P20068) In PDB | RATTUS NORVEGICUS (NORWAY RAT) |
Sequence modifications
A, B: 50 - 390 (UniProt: P20789)
C, D: 8 - 13 (UniProt: P20068)
PDB | External Database | Details |
---|---|---|
Gly 46 | - | expression tag |
Pro 47 | - | expression tag |
Gly 48 | - | expression tag |
Ser 49 | - | expression tag |
Thr 391 | - | expression tag |
Arg 392 | - | expression tag |
Glu 393 | - | expression tag |
Leu 394 | - | expression tag |
Glu 395 | - | expression tag |
Val 396 | - | expression tag |
Leu 397 | - | expression tag |
Phe 398 | - | expression tag |
Gln 399 | - | expression tag |
Gly 83 | Ser 83 | engineered mutation |
Leu 86 | Ala 86 | engineered mutation |
Arg 101 | Thr 101 | engineered mutation |
Asp 103 | His 103 | engineered mutation |
Tyr 105 | His 105 | engineered mutation |
Phe 119 | Leu 119 | engineered mutation |
Leu 121 | Met 121 | engineered mutation |
Asp 124 | Glu 124 | engineered mutation |
Lys 143 | Arg 143 | engineered mutation |
Glu 150 | Asp 150 | engineered mutation |
Val 161 | Ala 161 | engineered mutation |
Leu 167 | Arg 167 | engineered mutation |
Leu 213 | Arg 213 | engineered mutation |
Leu 234 | Val 234 | engineered mutation |
Arg 235 | Lys 235 | engineered mutation |
Leu 240 | Val 240 | engineered mutation |
Ala 253 | Ile 253 | engineered mutation |
Ala 260 | Ile 260 | engineered mutation |
Arg 262 | Asn 262 | engineered mutation |
Arg 263 | Lys 263 | engineered mutation |
- | Val 280 | deletion |
- | Gly 281 | deletion |
- | Thr 282 | deletion |
- | His 283 | deletion |
- | Asn 284 | deletion |
- | Gly 285 | deletion |
- | Leu 286 | deletion |
- | Glu 287 | deletion |
- | His 288 | deletion |
- | Ser 289 | deletion |
- | Thr 290 | deletion |
- | Phe 291 | deletion |
- | Asn 292 | deletion |
- | Met 293 | deletion |
- | Thr 294 | deletion |
- | Ile 295 | deletion |
Arg 305 | His 305 | engineered mutation |
Val 332 | Cys 332 | engineered mutation |
Ala 342 | Phe 342 | engineered mutation |
Ser 354 | Thr 354 | engineered mutation |
Val 358 | Phe 358 | engineered mutation |
Ala 362 | Ser 362 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly 4 | - | expression tag |
Pro 5 | - | expression tag |
Gly 6 | - | expression tag |
Gly 7 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 77370.7 | |
All* | Total formula weight | 77370.7 |