4BVE
CRYSTAL STRUCTURE OF HUMAN SIRT3 IN COMPLEX WITH THIOALKYLIMIDATE FORMED FROM THIO-ACETYL-LYSINE ACS2-PEPTIDE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-3, MITOCHONDRIAL | polymer | 284 | 31484.2 | 1 | UniProt (Q9NTG7) Pfam (PF02146) | HOMO SAPIENS (HUMAN) | HSIRT3, REGULATORY PROTEIN SIR2 HOMOLOG 3, SIR2-LIKE PROTEIN 3, SIRT3 |
| 2 | B (B) | ACETYL-COENZYME A SYNTHETASE 2-LIKE, MITOCHONDRIAL | polymer | 10 | 1805.9 | 1 | UniProt (Q9NUB1) | HOMO SAPIENS | THIO-ACETYL-LYSINE ACS2-PEPTIDE, ACETATE-COA LIGASE 2, ACETYL-COA SYNTHETASE 2, ACECS2, ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 1 |
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | E (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 6 | F (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 7 | G (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 8 | H, I (A, B) | water | water | 18.0 | 221 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 33290.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 365.1 | |
| All* | Total formula weight | 33655.2 |
